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Renal denervation (RDN) is associated with decreased plasma renin activity (PRA) and aldosterone levels in patients with hypertension, according to a recent study. RDN is thought to interrupt the sympathetic-mediated neurohormonal pathway as part of its mechanism of action to reduce blood pressure (BP), noted study authors Felix Mahfoud, MD, of Saarland University Hospital in Homburg/Saar, Germany, and colleagues.

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