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As one of the most studied miRNAs, miR-21 plays a general role in regulating a variety of physiological and pathological processes.25,26 Studies of embryonic stem cells and mesenchymal stem cells (MSCs) have shown that the levels of miR-21 increased substantially following the induction of differentiation, indicating that miR-21 might play important roles in stem cell differentiation and development.27 Among these ...
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