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Several case reports are available for intravitreal aflibercept,33–36 as well as a retrospective review of eight cases, all of which had PED.37 Although RPE tears have been suggested as being associated with anti-VEGF therapy, they were frequently described before the introduction of anti-VEGF treatment in high-risk patients with PED,5 with an incidence of 10% to 12% of eyes.38,39 This is slightly lower ...

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