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Since we found that Aβ levels were decreased in the brain tissues of 5xFAD;OGA +/− mice compared with 5xFAD mice, we further characterized the structural changes in the mitochondria in brain tissue samples from WT, WT;OGA +/− , 5xFAD, and 5xFAD;OGA +/− mice using high-resolution transmission electron microscopy (TEM).
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