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Note that, in recent years, HA nanoparticles (n-HA) were found to be capable of inhibiting proliferation and inducing apoptosis in various cancer cells ( 10 ) including osteosarcoma cells ( 11 ), breast cancer cells ( 12 ), gastric cancer cells ( 13 ), colon cancer cells ( 14 ), and liver cancer cells ( 15 ) but spare the normal cells.
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