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41598 2022 14297 Fig1 HTML.
Downregulation of cGAS expression correlates with poor prognosis in PDACs The importance of cGAS-STING signaling in cancer has been evidenced in many preclinical models, both in vivo and in vitro16,17,18,19. STING expression is often lost or downregulated in gastrointestinal tumors17,18,19.

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