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Increased pyroptosis is observed in tears of dry eye patients and hyperosmotic stress (HS)-stimulated human corneal epithelial cells in vitro, while inhibition of pyroptosis by disulfiram protects cells against HS-induced cell cytotoxicity To determine whether pyroptosis was involved in dry eye status, tears from dry eye patients were collected using Schirmer strips, and the expression of GSDMD, as well ...
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