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In a previous study only 23% of patients collected sufficient CD34+ cells with remobilization with G-CSF.15 Mobilization failure is associated with several factors including age, advanced disease, premobilization platelet count <100×109/L, multiple chemotherapy lines, previous radiotherapy, pretreatment with alkylating agents, purine analogs or immune-modulators, diabetes and smoking.4,7 The Italian Group for Stem Cell Transplantation GITMO (Gruppo Italiano Trapianto di Midollo Osseo) ...
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